The Collaborative Research Center for American Indian Health (CRCAIH—pronounced “KIRK-uh”) was formed in September 2012 with a grant from the National Institute for Minority Health and Health Disparities.
MISSION: The Collaborative Research Center for American Indian Health (CRCAIH) is designed to create a platform to bring together Tribal communities and health researchers from multiple disciplines, to work together in conducting cutting-edge transdisciplinary research that addresses significant health disparities experienced by American Indians in South Dakota, North Dakota, and Minnesota.
Our goal is to build tribal research infrastructure and promote transdisciplinary research teams to improve American Indian health through examination of social and environmental influences on health.
The Research Division provides leadership to support the implementation of three large-scale research projects designed to accelerate the discovery of new interventions and expand the utilization/adaptation of existing evidence-based interventions for preventing, reducing and ultimately eliminating health disparities.
- Factors Influencing Pediatric Asthma (Best - PI)
- Culturally Targeted Education on Living Kidney Donation (Fahrenwald - PI)
- Emergency Department Use and Care in American Indian Children (Puumala - PI)
The Research Division also monitors and assesses progress and accomplishments of all research projects to ensure adequate progress according to defined timelines.
Using a Community-Based Participatory Research approach, the Community Engagement and Innovation Division (CEID) works with tribal partners in developing or strengthening research infrastructure through:
- Coordinating community engagement activities to meet tribal research agenda goals
- Building community/tribal capacity by identifying community health priorities, trainings, working groups or information resources
- Working with Community Liaisons to develop strategies that meet the community's health and research endeavors to reduce or address the community's health disparities
The Regulatory Knowledge Core (RKC) ensures responsible research. The five RKC focus areas include:
- Providing regulatory support for communities and researchers
- Educating and training communities and researchers
- Monitoring and controlling the quality of research projects
- Developing tribal research capabilities
The Methodology Core (MC) consults on the planning and design stages of studies. It provides data management services and also trains tribal communities and researchers in current data management methods. The MC advises on:
- Study design
- Data collection form design
- Report generation
- Statistical analysis
The Culture, Science and Bioethics Core (CSBC) mission is to facilitate ethical research that meets the cultural and contextual needs of tribal communities within the CRCAIH region by bridging aspects of traditional, western/academic, and policy sciences. Its aims are to:
- Develop and integrate training modules on research for AI/AN communities and health researchers.
- Work to develop collaborative efforts between CRCAIH and NCAI that utilize CRCAIH cores and advance research in the ND/SD/MN region.
Help CRCAIH disseminate products and resources to a national audience
The Administrative Division provides leadership to:
- Ensure all CRCAIH milestones/goals are met in a timely fashion
- Facilitate engagement of partners through promotion of timely and effective communication
In addition to the oversight and fiscal responsibilities, the Administrative Division heads the Annual Summit, Pilot Grants Program, and Evaluation.
- Help tribes and health researchers build the strong relationships needed to plan and carry out research on regional AI health issues.
- Mentor tribes in all aspects of research, and provide technical assistance, so that the tribes can develop and conduct future research on their own.
- Support three innovative research projects that address identified regional AI health issues.
- Support and monitor a pilot grant program to fund research in line with CRCAIH goals.
AI/AN health issues
In the U.S., racial and ethnic minorities continue to have higher rates of disease and early death than the rest of the nation.
The American Indian / Alaska Native (AI/AN) population is the smallest U.S. racial and ethnic minority group. In spite of its small size, the AI/AN group has:
- The highest health risk factors of any racial minority
- The highest percentage of chronic disease of any racial minority
- A life expectancy lower than that of the general U.S. population
- A cancer mortality rate 40% higher than that of the general U.S. population
- A cardiovascular disease rate 100% higher than that of the general U.S. population
- An infant mortality rate 20% higher than the average rate for all minorities
Poverty, low levels of education, low socio-economic status, crime, and greater exposure to environmental hazards all contribute to the health crisis of the AI/AN population. In addition, there are regional health differences between AI populations.
In many studies, Northern Plains tribes have worse health and more chronic illness than tribes in the southern U.S.
All CRCAIH research projects will be transdisciplinary. Transdisciplinary research uses the involvement of many disciplines and perspectives to create new practices and problem-solving methods.
CRCAIH project experts will include:
- Tribal health administrators
- Spiritual leaders
- Academic health researchers in a wide variety of disciplines
- Healthcare providers in a wide variety of disciplines
CRCAIH is one of the National Institute of Health's Transdisciplinary Collaborative Centers for Health Disparities Research funded projects. For more information on Transdisciplinary Collaborative Centers click here.
Elliott, A. J., White Hat, E. R., Angal, J., Grey Owl, V., Puumala, S. E., & Baete Kenyon, D. (2015). Fostering Social Determinants of Health Transdisciplinary Research: The Collaborative Research Center for American Indian Health. International Journal of Environmental Research and Public Health, 13(1). doi: 10.3390/ijerph13010024. PMID: 26703683
Horst Hauge, C., Jacobs-Knight, J., Jenson, J. L., Burgess, K. M., Puumala, S. E., Wilton, G., & Hanson, J. D. (2015). Establishing survey validity and reliability for American Indians through “think aloud” and test-retest methods. Qualitative Health Research, 25(6). 820-830. doi: 10.1177/1049732315582010. PMID: 25888693
Puumala, S.E., Burgess, K. M., Karbanda, A. B., Zook, H. G., Castille, D. M., Pickner, W. J., & Payne, N. R. (2016). The Role of Bias by Emergency Department Providers in Care for American Indian Children. Medical Care, 54(6). 562-569. doi: 10.1097/MLR.0000000000000533. PMID: 26974675
Zook, H. G., Karbanda, A. B., Flood, A., Harmon, B., Puumala, S. E., & Payne, N. R. (2016). Racial Differences in Pediatric Emergency Department Triage Scores. The Journal of Emergency Medicine, 50(5). 720-727. doi: 10.1016/j.jemermed.2015.02.056. PMID: 26899520
Best, L. G., O’Leary, R. A., O’Leary, M. A., & Yracheta, J. M. (2016). Humoral immune factors and asthma among American Indian children: a case-control study. BMC Pulmonary Medicine, 16(93). doi: 10.1186/s12890-016-0257-6 PMID: 27295946
Villegas, M., Around Him, D., Lucero, J. E., & Pytalski, S. C. (2016). All Our Relations: Assuring Tribal Research Ethics from Generation to Generation. Journal of Healthcare, Science and the Humanities, 6(1). 50-66. Retrieved from http://tuskegeebioethics.org/wp-content/uploads/2015/01/JHSH-V6n1-Fall-Spring2016-spreads-FINAL3-2.pdf#page=29
Pickner, W. J., Puumala, S. E., Chaudhary, K. R., Burgess, K. M., Payne, N. R., & Karbanda, A. B. (2016). Emergency Department Utilization for Mental Health in American Indian Children. The Journal of Pediatrics, 174. 226-231. doi: 10.1016/j.jpeds.2016.03.064. PMID: 27131404
Zook, H. G., Kharbanda, A. B., Puumala, S. E., Burgess, K. M., Pickner, W. J., & Payne, N. R. (2017). . Emergency Department Utilization by Native American Children. Pediatric Emergency Care. doi: 10.1097/pec.0000000000001289. PMID: 28953102
Angal, J., Petersen, J. M., Tobacco, D., & Elliott, A. J. (2016). Ethics Review for a Multi-Site Project Involving Tribal Nations in the Northern Plains. Journal of Empirical Research on Human Research Ethics, 11(2). 91-96. doi: 10.1177/1556264616631657.
Hanson, J. D., Jensen, J. L., Campbell, K., Chaudhary, K. R., & Puumala, S. E. (2016). Epidemiology of substance-exposed pregnancies at one Great Lakes hospital that serves a large number of American Indians. American Indian & Alaska Native Mental Health Research: The Journal of the National Center, 23(4). 44-62. doi: 10.5820/aian.2304.2016.44. PMID: 27536897
Zook, H. G., Payne, N. R., Puumala, S. E., Burgess, K. M., & Kharbanda, A. B. (2016). Racial/Ethnic Variation in Emergency Department Care for Children with Asthma. Pediatric Emergency Care.
Hanson, J. D., Nelson, M. E., Jensen, J. L., Willman, A., Jacobs-Knight, J., & Ingersoll, K. (2017). Impact of the CHOICES Intervention in Preventing Alcohol-Exposed Pregnancies in American Indian Women. Alcoholism Clinical & Experimental Research, 41(4), 828-835. doi: 10.1111/acer.13348
Best, L.G., Azure, C., Segarra, A., Enright, K.J., Hamley, S., Jerome, D., O'Leary, M.A., O'Leary, R.A., Parisien, A., Trottier, K., Yracheta, J.M., Torgerson, D.G. Genetic variants and risk of asthma in an American Indian population. (2017). Annals of Allergy Asthma and Immunology. 119(1):31-36.e1. doi:10.1016/j.anai.2017.05.015.
Running Bear, U., Beals, J., Kaufman, C.E., Manson, S.M. (2017). Boarding School Attendance and Physical Health Status of Northern Plains Tribes. Applied Research in Quality of Life. doi: 10.1007/s11482-017-9549-0.
Download CRCAIH info sheet (version 032017)